Achalasia is typically diagnosed in adults, but can occur in children as well. There is no particular race or ethnic group that is affected,
and the condition does not run in families. Three tests are most commonly used to diagnose and evaluate a swallowing problem:
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Barium swallow: The patient swallows a barium preparation (liquid or other form) and its movement the esophagus is evaluated using X-ray.
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Endoscopy: A flexible, narrow tube called an endoscope is passed into the esophagus and projects images of the inside of the esophagus onto a screen.
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Manometry: This test measures the timing and strength of esophageal (pump) contractions and lower esophageal sphincter (valve) relaxation.
If left untreated, achalasia can be debilitating. People with the condition experience considerable weight loss that can result in malnutrition.
Lung infections and pneumonia due to aspiration of food can result, particularly in the elderly. Although the exact cause of achalasia is unknown,
researchers think it may be linked to a virus.
There are several successful treatments available for achalasia, including:
Minimally
Invasive Surgery Today, select patients with achalasia can be treated successfully by a minimally invasive surgical technique
called laparoscopic esophagomyotomy. Using five small incisions, a myotomy can be accomplished (called laparoscopic myotomy).
It has been shown that the addition of a partial fundoplication minimizes reflux and protects the esophagus from damaging gastroesophageal
reflux. This operation usually requires one day of hospital stay and recovery is typically accelerated when compared to conventional surgery.
Up to two-third of patients are treated successfully with surgery, though some patients may have to repeat the surgery or undergo balloon dilation
to achieve satisfactory long-term results.
Pneumatic (Balloon) dilation
Occasionally, achalasia can be treated non-surgically with balloon dilation. While the patient is under light sedation, the gastroenterologist inserts
a specially designed balloon through the lower esophageal sphincter and inflates it. The balloon disrupts the esophageal muscle and widens the opening
for food to enter the stomach. Some patients may have to undergo repeated dilation treatments in order to achieve symptom improvement, and the treatment
may have to be repeated every few years to ensure long-term results.
Surgery
In this operation, the muscles of the valve between the esophagus into the stomach are cut. Traditionally,
the myotomy is completed through an open incision in the abdomen or through an incision in the left side of the chest between the ribs. These types of incisions often required hospitalization of up to a week for adequate recovery.
Medication
Patients who are not appropriate candidates for balloon dilation or surgery may benefit from botulinum toxin (Botox) injections. Botox is a protein made by the bacteria that cause botulism. When injected into muscles in very small quantities, Botox can relax spastic muscles. It works by preventing nerves from sending signals to the muscles that tell them to contract. A smaller percentage of patients achieve good short-term results using Botox compared to balloon dilation. In addition, the injections must be repeated frequently in order to achieve symptom relief.
It must be remembered that treatment of achalasia does not fix the esophagus, it only attempts to improve esophageal emptying. This, however, is at the risk of allowing the stomach to empty it contents into the esophagus (reflux).
Regardless of the therapy, long-term follow up is necessary to assure that the esophagus can be preserved as a passive conduit. This requires adequate esophageal emptying after the treatment of choice and prevention of gastro-esophageal reflux. The obstructed esophagus or one that is subjected to reflux will dilate and expand and may eventually need to be replaced.