Health A to Z

Achalasia

Achalasia is a condition where the esophagus is unable to move food into the stomach. The esophagus is the muscular tube that extends from the neck to the abdomen and connects the throat to the stomach. The lower esophageal sphincter (LES), a valve located at the end of the esophagus, stays closed during swallowing, resulting in the back up of food. Other symptoms include vomiting undigested food, chest pain, heartburn and weight loss.


Slowly, over a number of years, people with achalasia experience an increasing difficulty in eating solid food and in drinking liquids. As their condition advances, achalasia can cause considerable weight loss and malnutrition. People with achalasia also have a small increase in the risk of developing esophageal cancer, particularly if the obstruction has been present for a long time. Regular endoscopic screenings are recommended for the prevention and early detection of esophageal cancer.


Cause of esophageal muscles failing to contract normally in people with motility disorders, including achalasia, is unknown. Researchers think it may be linked to a virus, and recent studies show achalasia is caused by nerve cells of the instinctive nervous system within the muscle layers of the esophagus. They are attacked by the patient’s own immune system and slowly degenerate for reasons that are not currently understood.


Achalasia is a persistent problem, causing symptoms lasting months or years. People who experience only a brief episode of symptoms, such as difficulty swallowing, typically do not have a true esophageal motility disorder.


The main symptoms of achalasia include:
  • 1) Difficulty swallowing (dysphagia)
  • 2) Regurgitation of undigested bitter food
  • 3) Chest pain
  • 4) Heartburn

Achalasia is typically diagnosed in adults, but can occur in children as well. There is no particular race or ethnic group that is affected, and the condition does not run in families. Three tests are most commonly used to diagnose and evaluate a swallowing problem:


  • Barium swallow: The patient swallows a barium preparation (liquid or other form) and its movement the esophagus is evaluated using X-ray.
  • Endoscopy: A flexible, narrow tube called an endoscope is passed into the esophagus and projects images of the inside of the esophagus onto a screen.
  • Manometry: This test measures the timing and strength of esophageal (pump) contractions and lower esophageal sphincter (valve) relaxation.

If left untreated, achalasia can be debilitating. People with the condition experience considerable weight loss that can result in malnutrition. Lung infections and pneumonia due to aspiration of food can result, particularly in the elderly. Although the exact cause of achalasia is unknown, researchers think it may be linked to a virus.


There are several successful treatments available for achalasia, including:


Minimally


Invasive Surgery Today, select patients with achalasia can be treated successfully by a minimally invasive surgical technique called laparoscopic esophagomyotomy. Using five small incisions, a myotomy can be accomplished (called laparoscopic myotomy). It has been shown that the addition of a partial fundoplication minimizes reflux and protects the esophagus from damaging gastroesophageal reflux. This operation usually requires one day of hospital stay and recovery is typically accelerated when compared to conventional surgery. Up to two-third of patients are treated successfully with surgery, though some patients may have to repeat the surgery or undergo balloon dilation to achieve satisfactory long-term results.


Pneumatic (Balloon) dilation


Occasionally, achalasia can be treated non-surgically with balloon dilation. While the patient is under light sedation, the gastroenterologist inserts a specially designed balloon through the lower esophageal sphincter and inflates it. The balloon disrupts the esophageal muscle and widens the opening for food to enter the stomach. Some patients may have to undergo repeated dilation treatments in order to achieve symptom improvement, and the treatment may have to be repeated every few years to ensure long-term results.


Surgery


In this operation, the muscles of the valve between the esophagus into the stomach are cut. Traditionally, the myotomy is completed through an open incision in the abdomen or through an incision in the left side of the chest between the ribs. These types of incisions often required hospitalization of up to a week for adequate recovery.


Medication


Patients who are not appropriate candidates for balloon dilation or surgery may benefit from botulinum toxin (Botox) injections. Botox is a protein made by the bacteria that cause botulism. When injected into muscles in very small quantities, Botox can relax spastic muscles. It works by preventing nerves from sending signals to the muscles that tell them to contract. A smaller percentage of patients achieve good short-term results using Botox compared to balloon dilation. In addition, the injections must be repeated frequently in order to achieve symptom relief.


It must be remembered that treatment of achalasia does not fix the esophagus, it only attempts to improve esophageal emptying. This, however, is at the risk of allowing the stomach to empty it contents into the esophagus (reflux).


Regardless of the therapy, long-term follow up is necessary to assure that the esophagus can be preserved as a passive conduit. This requires adequate esophageal emptying after the treatment of choice and prevention of gastro-esophageal reflux. The obstructed esophagus or one that is subjected to reflux will dilate and expand and may eventually need to be replaced.

ADHD

Attention deficit hyperactivity disorder (ADHD) is a common condition that affects children and adolescents and can continue into adulthood for some. ADHD may occur in 8% to 10% of school children. It is also question whether kids really outgrow ADHD. It means that this disorder may be more common in adults than previously thought.


Children with ADHD generally have problems paying attention. They can't seem to follow directions and are easily bored with assigned tasks. They also tend to move constantly and are impulsive, not stopping to think before they act. These behaviors are generally common in children. But they occur more often than usual and are more severe in a child with ADHD. The behaviors that are common with ADHD interfere with a child's ability to function at school and at home.


Adults with ADHD may have difficulty with time management, organizational skills, target setting, and employment. They may also have issues with relationships, self-esteem, and addictions.


What causes ADHD?


The exact cause of ADHD is unknown. Experts continue to study the brain for its evidence. They suspect that there are several factors that may contribute to the condition, including:


  • 1) Brain changes: Areas of the brain that control attention are less active in children with ADHD than in children without ADHD.
  • 2) Chemical imbalance:Experts believe an inequity of neurotransmitters that transmit nerve impulses may be a factor in the development of ADHD symptoms.
  • 3) Heredity: The fact that ADHD tends to run in families suggests that children may inherit a tendency to develop ADHD from their parents.

The symptoms of ADHD include inattention and/or hyperactivity and impulsivity. These are traits that most people display at some point or another. Approximately half of adults diagnosed with the disorder had it as children. When ADHD persists into adulthood, symptoms may vary. For instance, an adult may experience restlessness instead of hyperactivity. Adults with ADHD have issues with interpersonal relationships and employment.


Types of ADHD


The exact cause of ADHD is unknown. Experts continue to study the brain for its evidence. They suspect that there are several factors that may contribute to the condition, including:


  • Combined ADHD: It involves symptoms of both inattentiveness and hyperactivity
  • Inattentive ADHD: It is marked by impaired concentration and attentiveness
  • Hyperactive-impulsive ADHD, which is marked by hyperactivity without inattentiveness

Symptoms of ADHD


  • 1) A person with ADHD may have some or all of the following symptoms:
  • 2) Difficulty paying attention to details
  • 3) Tendency to make casual mistakes; producing work that is often disorganized
  • 4) Easily distracted by irrelevant stimuli and frequently interrupting ongoing tasks to attend to trivial noises or events that are usually ignored by others
  • 5) Inability to sustain attention on tasks or activities
  • 6) Difficulty finishing work or performing tasks that require concentration
  • 7) Frequent shifts from one uncompleted activity to another
  • 8) Forgetfulness in daily activities
  • 9) Failure to complete tasks at home or/and at work
  • 10) Frequent shifts in conversation, not listening to others, not keeping one's mind on conversations, and not following details or rules of activities in social situations

For a diagnosis of ADHD, some symptoms that cause impairment must be present before age seven. Also, some impairment from the symptoms must be present in more than one setting. For instance, the person may be impaired at home or/and work. Also, there must be clear evidence the symptoms interfere with the person's ability to function at home, in social setup, or at work.

Aesthetic

As the skin ages, it gradually loses some of its collagen and fat. These are the materials that prevent the skin from becoming saggy. Thus, as we age, our skin can become thinner and more wrinkled and lined. Dermal fillers help to restore skin to its earlier young appearance. Material is injected into the skin in areas where it needs to be plumped up again and made to look firmer. Common areas for treatment with dermal fillers include; lips, cheeks, tear troughs, chin, nose, brows, mouth corners, and wrinkles (static wrinkles).


Dermal fillers are made of various kinds of natural or synthetic materials that have been developed over the years for injection into the skin. It comes in different thicknesses, and in general, the thicker the product, the deeper it is injected into the dermal layer of the skin to help plump out fine to deep lines and wrinkles, such as naso-labial folds (nose to mouth lines), fill scars, contour the cheeks and chin or augment lips.


Dermal fillers tend to be broadly classified as being either non-permanent (restorable) or permanent (non-restorable) in their effect. Other non-permanent fillers to be developed include ones using polylactic acid and calcium hydroxylapatite. Permanent fillers are not widely used but can give a longer lasting effect, or even a permanent effect, and may be recommended in some cases.


Rhytidectomy commonly known as facelift is a type of cosmetic surgery used to give a more youthful facial appearance. There are multiple surgical techniques. It usually involves the removal of excess facial skin, with or without the tightening of underlying tissues, and the redraping of the skin on the patient's face and neck.


Sagging or wrinkled skin occurs naturally with increasing age. Folds and fat deposits appear around the neck, and deep creases form between the nose and mouth. The jaw line grows jowly and slack. Genetics, deprived diet, smoking, or obesity can contribute to early or severe skin problems.


As a restorative surgery, a facelift does not change primary appearance and cannot stop the aging process. It can help repair some of the evident signs of aging. Fixing damage to skin, fat, and muscles can reinstate a younger look.


A facelift can only be performed surgically; non-surgical rejuvenation treatments cannot achieve the same results, but may help delay the time at which a facelift becomes appropriate and complement the results of surgery.

Allergies

Allergic rhinitis commonly known as hay fever is the most common of the allergic diseases and refers to seasonal nasal symptoms that are due to pollens. Year round or perennial allergic rhinitis is usually due to indoor allergens, such as dust mites, animal dander, or molds. It can also be caused by pollens. Symptoms result from the inflammation of the tissues that line the inside of the nose (mucus lining or membranes) after allergens are inhaled. Adjacent areas, such as the ears, sinuses, and throat can also be involved.


The most common symptoms include:


  • 1) Nasal itching
  • 2) Runny nose
  • 3) Sneezing
  • 4) Itchy ears and throat

Types of Rhinitis:


  • 1) Infective rhinitis which includes acute and chronic bacterial infections;
  • 2) Non-allergic (vasomotor) rhinitis which includes autonomic, hormonal, drug-induced, atrophic, and gustatory rhinitis
  • 3) Allergic rhinitis, triggered by pollen, mold, animal dander, dust and other similar inhaled allergens

Rhinitis is commonly caused by a viral or bacterial infection, including the common cold. Symptoms of the common cold include rhinorrhea, sore throat, cough, congestion, and headache

Asthma is a lung disease affecting the airways that carry air to and from lungs. People who suffer from this chronic condition (long-lasting or recurrent) are said to be asthmatic.


Asthma is caused by a combination of complex environmental and genetic factors. These factors influence both its severity and its responsiveness to treatment. It is believed that the recent increased rates of asthma are due to changing heritable factors and changing living environment.


Asthma Attack & its consequences:

An asthma attack is when symptoms are worse than usual. They can come on suddenly and can be mild, moderate or severe.

  • The muscles around your airways tighten up, narrowing the airway.
  • Less air is able to flow through the airway.
  • Inflammation of the airways increases
  • Surge in production of mucus in the airways, affecting the flow of air

An Asthmatic should see your doctor on timely basis. This way one can find out what triggers asthma symptoms and how to avoid them. Prescribed medications help in management of asthma.

Adverse reactions to drugs are common. Drug allergies are a group of symptoms caused by an allergic reaction to a drug. Almost any drug can cause an adverse reaction. Reactions range from irritating or mild side effects such as nausea and vomiting to life-threatening anaphylaxis.


A true drug allergy is caused by a series of chemical steps in the body that produce the allergic reaction to a drug. This happens when the body believes the drug is a foreign substance that is dangerous. The body tries to attack the drug with histamine and other substances in order to expel it from the body. A drug allergy may also occur without your body producing histamine. Instead, it might produce other types of antibodies, or have other reactions that do not produce antibodies.


Asthma Attack & its consequences:


Penicillin and related antibiotics are the most common cause of drug allergies. Other common allergy-causing drugs include:

  • Anticonvulsants
  • Insulin
  • Iodinated x-ray contrast dyes
  • Sulfa drugs

Common Symptoms:

  • Hives
  • Itching of the skin or eyes
  • Skin rash
  • Swelling of the lips, tongue, or face
  • Wheezing

Prevention of Drug Allergies:


There is generally no way to prevent a drug allergy. If you have a known drug allergy, avoiding the drug is the best way to prevent an allergic reaction.

Your health care provider may also recommend "desensitization." This procedure must be done under close medical supervision. It involves giving very small doses of the medicine over a specific period of time. Do not try this without your health care provider's supervision.

Alzheimer's

Alzheimer's disease is the most common form of dementia among older people. Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities. The main risk factor for Alzheimer's disease is increased age. As a population ages, the frequency of Alzheimer's disease continues to increase. It first involves the parts of the brain that control thought, memory and language. Patients may have trouble remembering things that happened recently or names of people they know. A related problem, mild cognitive impairment (MCI), causes more memory problems than normal for people of the same age. Many, but not all, people with MCI will develop Alzheimer’s.


Other risk factors for Alzheimer's disease include high blood pressure (hypertension), coronary artery disease, diabetes, and possibly elevated blood cholesterol. Individuals who have completed less than eight years of education also have an increased risk for Alzheimer's disease.


Symptoms get worse over time. People may not recognize family members or have trouble speaking, reading or writing. Eventually, they need total care.


A facelift can only be performed surgically; non-surgical rejuvenation treatments cannot achieve the same results, but may help delay the time at which a facelift becomes appropriate and complement the results of surgery.

Aithritis

Alzheimer's disease is the most common form of dementia among older people. Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities. The main risk factor for Alzheimer's disease is increased age. As a population ages, the frequency of Alzheimer's disease continues to increase. It first involves the parts of the brain that control thought, memory and language. Patients may have trouble remembering things that happened recently or names of people they know. A related problem, mild cognitive impairment (MCI), causes more memory problems than normal for people of the same age. Many, but not all, people with MCI will develop Alzheimer’s.


Other risk factors for Alzheimer's disease include high blood pressure (hypertension), coronary artery disease, diabetes, and possibly elevated blood cholesterol. Individuals who have completed less than eight years of education also have an increased risk for Alzheimer's disease.


Symptoms get worse over time. People may not recognize family members or have trouble speaking, reading or writing. Eventually, they need total care.


A facelift can only be performed surgically; non-surgical rejuvenation treatments cannot achieve the same results, but may help delay the time at which a facelift becomes appropriate and complement the results of surgery.

Arthritis is a form of joint disorder that involves inflammation of one or more joints. The most common form, osteoarthritis (degenerative joint disease), is a result of trauma to the joint, infection of the joint, or age. Other arthritis forms are rheumatoid arthritis, psoriatic arthritis, and related autoimmune diseases. Septic arthritis is caused by joint infection.


The pain from arthritis is due to inflammation that occurs around the joint, damage to the joint from disease, daily wear and tear of joint, muscle strains caused by forceful movements against stiff painful joints and fatigue. The major complaint by individuals who have arthritis is joint pain. Pain is often a constant and may be localized to the joint affected


Adults with ADHD may have difficulty with time management, organizational skills, target setting, and employment. They may also have issues with relationships, self-esteem, and addictions.


Common symptoms:


Regardless of the type of arthritis, the common symptoms for all arthritis disorders include varied levels of pain, swelling, joint stiffness, and sometimes a constant ache around the joint(s). Some common symptoms are given as under:


  • 1) Inability to use the hand or walk
  • 2) Muscle weakness
  • 3) Loss of flexibility
  • 4) Decreased aerobic fitness
  • 5) Weight loss
  • 6) Poor sleep
  • 7) Muscle aches and pains
  • 8) Tenderness

Arthritis is a form of joint disorder that involves inflammation of one or more joints. The most common form, osteoarthritis (degenerative joint disease), is a result of trauma to the joint, infection of the joint, or age. Other arthritis forms are rheumatoid arthritis, psoriatic arthritis, and related autoimmune diseases. Septic arthritis is caused by joint infection.

There are over 100 types of arthritis. Here is a description of some common ones, together with the causes:


Osteoarthritis

cartilage loses its elasticity. The cartilage, which acts as a shock absorber, will gradually wear away in some areas. As the cartilage becomes damaged tendons and ligaments become stretched, causing pain. Eventually the bones may rub against each other causing very severe pain.


Rheumatoid arthritis :

this is an inflammatory form of arthritis. The synovial membrane is attacked, resulting in swelling and pain. If left untreated the arthritis can lead to deformity. Rheumatoid arthritis is significantly more common in women than men and generally strikes when the patient is aged between 40 and 60. However, children and much older people may also be affected.


Infectious arthritis (septic arthritic)

It is usually caused by bacteria, but could also be caused by fungi or viruses. Bacteria, fungi or viruses may spread through the bloodstream from infected tissue nearby, and infect a joint. Most susceptible people are those who already have some form of arthritis and develop an infection that travels in the bloodstream.


Juvenile rheumatoid arthritis (JRA) –

JRA means arthritis that affects a person aged 16 or less. JRA can be various forms of arthritis. There are three main types:


  • 1) Pauciarticular JRA, the most common and mildest. The child experiences pain in up to 4 joints.
  • 2) Polyarticular JRA affects more joints and is more severe. As time goes by it tends to get worse.
  • 3) Systemic JRA is the least common. Pain is experienced in many joints. It can spread to organs. This can be the most serious JRA.

Autism

Autistic disorder (ASD) is the most common condition in a group of developmental disorders known as the autism spectrum disorders (ASDs). Autism varies widely in its severity and symptoms and may go unrecognized, especially in mildly affected children or when more debilitating handicaps mask it. Scientists aren’t certain what cause autism, but it’s likely that both genetics and environment play a role. Autistic children have difficulties with social interaction, display problems with verbal and nonverbal communication, and exhibit repetitive behaviors or narrow, obsessive interests. These behaviors can range in impact from mild to disabling.


There is no cure for autism. Therapies and behavioral interventions are designed as per specific symptoms and can bring about considerable progress. The ideal treatment plan coordinates therapies and interventions that meet the specific needs of the individual. Treatment options include educational/behavioral interventions, medications, and other therapies. Experts agree that the earlier the intervention, the better.


For many children, autism symptoms improve with treatment and with age. Some children with autism grow up to lead normal or near-normal lives. Children, whose language skills regress early in life, usually before the age of 3, appear to be at risk of developing epilepsy or seizure-like brain activity. During adolescence, some children with autism may become depressed or experience behavioral problems. Parents of these children should be ready to adjust treatment for their child as needed. People with an ASD usually continue to need services and support as they get older but many are able to work successfully and live independently or within a supportive environment.